Black cohosh (Actaea racemosa) for the mitigation of menopausal symptoms: recent developments in clinical safety and efficacy

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Analysis of formononetin from black cohosh (Actaea racemosa).

Black cohosh has been widely used as an herbal medicine for the treatment of symptoms related to menopause in America and Europe during the past several decades, but the bioactive constituents are still unknown. Formononetin is an isoflavone with known estrogen-like activity. This compound was first reported to be isolated from black cohosh in 1985, but subsequent research in 2002 using HPLC-PD...

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Recovery of Black Cohosh (Actaea racemosa L.) Following Experimental Harvests

—Since European colonization and subsequent commercialization of Appalachian medicinal and edible plants, millions of kilograms of plant material have been extracted from our forests, with little effort to manage these species as natural resources. Roots and rhizomes of black cohosh, a native Appalachian forest herb, are extensively harvested for treatment of menopausal symptoms. As nearly all ...

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The non-estrogenic alternative for the treatment of climacteric complaints: Black cohosh (Cimicifuga or Actaea racemosa).

In postmenopausal women estrogens in combination with progestins have beneficial effects on climacteric complaints and on osteoporosis but this hormone replacement therapy (HRT) bears the risk of increased mammary carcinomas and cardiovascular diseases. Phytoestrogens at low doses have little or no effects on climacteric complaints, at high doses they mimic the effects of estrogens. Therefore o...

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Evaluation of Extraction Methods for Isolation and Detection of Formononetin in Black Cohosh (Actaea racemosa L.)

Black cohosh (Actaea racemosa L.) is a medicinal plant from which extracts of the roots and rhizomes (commonly known as rhizomes) have become a popular remedy for the relief of menopausal symptoms. While the chemical constituents responsible for the medicinal properties of the plant are unknown, extracts of the rhizomes are known to contain cycloartane triterpene glycosides, phenolics, and flav...

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Commentary on black cohosh for the treatment of menopausal symptoms.

Black cohosh has central opioid activity in postmenopausal women: evidence from naloxone blockade and positron emission tomography neuroimaging. Abstract To test whether black cohosh (BC) exhibits an action on the central endogenous opioid system in postmenopausal women. This was a mechanistic study conducted in the same individuals of luteinizing hormone pulsatility with a saline/naloxone chal...

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ژورنال

عنوان ژورنال: Women's Health

سال: 2006

ISSN: 1745-5057,1745-5065

DOI: 10.2217/17455057.2.5.773